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Past, Present, and Future of RNA Modifications in Infectious Disease Research
In early 2024, the National Academies of Sciences, Engineering, and Medicine (NASEM) released a roadmap for the future of research into …
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Tracking the uptake of labelled host-derived extracellular vesicles by the human fungal pathogen Aspergillus fumigatus
Extracellular vesicles (EVs) have gained attention as facilitators of intercellular as well as interkingdom communication during …
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RNA-Biologie von Pilzinfektionen
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RNA:DNA triplexes: a mechanism for epigenetic communication between hosts and microbes?
Molecular communication between host and microbe is mediated by the transfer of many different classes of macromolecules. Recently, the …
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RNA as a mediator of host-fungal pathogenesis
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Elucidation of the Aspergillus fumigatus tRNA-derived RNA repertoire from conidia and mycelium
Aspergillus fumigatus is a ubiquitous filamentous fungus that causes devastating infections in severely immunocompromised individuals …
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Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences
The opportunistic fungal pathogen Candida albicans damages host cells via its peptide toxin, candidalysin. Before secretion, …
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Mod5 mediates a molecular trade-off between optimal gene expression and antifungal resistance.
Increasing antifungal drug resistance is a major concern associated with human fungal infections. Genetic mutation and epimutation …
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RNA-based sensitive fungal pathogen detection
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Disruption of the Aspergillus fumigatus RNA inteference machinery alters the conidial transcriptome.
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