Journal article

An Improved Description of the Small RNA Landscape of the Human Fungal Pathogen Aspergillus fumigatus
Aspergillus fumigatus is a ubiquitous filamentous fungus and dangerous human pathogen that produces a limited pool of small RNAs under …
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Comprehensive mapping of the 5' and 3' untranslated regions of Aspergillus fumigatus reveals diverse mechanisms of mRNA processing including premature transcription termination
In the twenty years since the first genome sequencing of Aspergillus fumigatus, the field has seen an explosion in both the number of …
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tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.
Increasing antifungal drug resistance is a major concern associated with human fungal pathogens like Aspergillus fumigatus. Genetic …
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Past, Present, and Future of RNA Modifications in Infectious Disease Research
In early 2024, the National Academies of Sciences, Engineering, and Medicine (NASEM) released a roadmap for the future of research into …
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Tracking the uptake of labelled host-derived extracellular vesicles by the human fungal pathogen Aspergillus fumigatus
Extracellular vesicles (EVs) have gained attention as facilitators of intercellular as well as interkingdom communication during …
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RNA:DNA triplexes: a mechanism for epigenetic communication between hosts and microbes?
Molecular communication between host and microbe is mediated by the transfer of many different classes of macromolecules. Recently, the …
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Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences
The opportunistic fungal pathogen Candida albicans damages host cells via its peptide toxin, candidalysin. Before secretion, …
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Disruption of the Aspergillus fumigatus RNA inteference machinery alters the conidial transcriptome.
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Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis
BACKGROUND. The fungus Aspergillus fumigatus causes a variety of clinical phenotypes in patients with cystic fibrosis (pwCF). T-helper …
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A tRNA modifying enzyme as a tunable regulatory nexus for bacterial stress responses and virulence
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